thompson44
Joined: 28 Dec 2020
Posts: 2
Posted: 2020-12-28 08:49
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abiraterone
Prostate cancer is one of the most common malignant tumors in men. In recent years, the incidence of prostate cancer in China has been on the rise, and most of it is in the middle and late stages when it is discovered. Studies have shown that androgens play an important role in the development of prostate cancer.
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At present, first-line endocrine therapy (including surgery, chemical anti-androgen castration or combined androgen blockade therapy) is the standard treatment mode for initial treatment of advanced prostate cancer, although this treatment method is effective for most patients in the initial stage. However, after a median treatment time of 14-30 months, almost all patients will gradually develop into castration-resistant prostate cancer (CRPC), with a median survival time of 1 to 2 years. Although docetaxel has been approved for first-line chemotherapy for CRPC, the treatment method is single. Once docetaxel fails, there is no effective treatment method. At the same time, some patients cannot tolerate the toxicity of chemotherapy, so this category Patients still need new effective and less toxic treatments. Abiraterone acetate (Zytiga) is a prodrug of
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, which is rapidly converted into abiraterone in the body, which is a selective and irreversible steroid of CYP17 (17α-hydroxylase and C17,20-lyase) Body inhibitors that inhibit the synthesis of testosterone in the testes, adrenal glands and tumors by inhibiting enzyme activity. This product is held by Johnson & Johnson and was first approved by the US FDA on April 28, 2011. It is used in combination with prednisone or prednisolone for the treatment of androgen castration therapy and docetaxel chemotherapy failure in patient Castration-resistant metastatic prostate cancer (mCRPC) was later approved on December 10, 2012 to expand the indication population for the treatment of castration-resistant advanced metastatic prostate cancer. The approved indication of this product in my country is "combined treatment with prednisone for metastatic castration-resistant prostate cancer (mCRPC)". Dosage: 1g once a day, not taken with food. The recommended dose of prednisone or prednisolone is 10 mg per day. We offer
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Redfearn
Joined: 15 Mar 2021
Posts: 2
Posted: 2021-04-12 12:03
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sajjada
Joined: 26 Sep 2021
Posts: 14
Posted: 2021-11-17 07:33
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laakea
Joined: 20 Apr 2021
Posts: 1103
Posted: 2022-01-20 13:14
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-21 08:20
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One of Us. What is a Real Life Superhero? Real Life Superheroes was established years ago to provide support and information for current and aspiring RLSH.
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-21 14:55
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Now, you may be thinking: How to start a payment processing company? Maybe you've been a salesperson for awhile—maybe you've even been selling POS equipment and other important retail tools—but you're not sure how to make that leap into selling for yourself
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Mediation
Joined: 21 Jan 2022
Posts: 1
Posted: 2022-01-21 21:54
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We usually occur such kinds of issues in our company, but there is no need to worry because we have lots of technical persons to resolve the problems.
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goalken
Joined: 08 Jul 2020
Posts: 115
Posted: 2022-01-22 08:49
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I'm in the same boat as you; I've searched Google for hours and hours and still haven't found anything; does anybody have any information that they could share with us? Thank you very much.
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-22 17:38
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-22 18:27
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Holly Lewis
Joined: 02 Sep 2021
Posts: 870
Posted: 2022-01-23 19:45
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firisi1000
Joined: 04 Dec 2021
Posts: 2424
Posted: 2022-01-24 13:53
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Holly Lewis
Joined: 02 Sep 2021
Posts: 870
Posted: 2022-01-25 14:00
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-26 21:54
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jognahartu
Joined: 06 Dec 2021
Posts: 2264
Posted: 2022-01-26 22:33
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